Stack Archive · Specialized Directory

Biohacking

Data-driven physiological optimization — wearables, protocols, and the clinical research behind what actually moves your biomarkers.

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Oct 26updated
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Scientists Reversed 'Permanent' Aging Damage in Human Tissue. Here's What Was Fixed.

A Nature Communications study showed an engineered enzyme (CMLase) removed advanced glycation end products from human arterial, skin, and lens tissue — reversing damage long considered irreversible.

· 3 min

Google's SensorFM: What a 1-Trillion-Minute Wearable Dataset Changes

Google's new foundation model for wearable sensors outperformed prior models on 34 of 35 health tasks — and what it means for the future of passive health monitoring.

· 3 min

Does Losing Sleep Mean Losing Lifespan? What the Meta-Analysis Can't Tell You

A new 79-study meta-analysis links short sleep to 14% higher mortality — but Peter Attia identifies a fundamental problem with the data. Here's what the observational evidence actually proves, and what the controlled research says instead.

· 3 min

The $10 Billion Probiotic Problem: What the Evidence Shows and What Works Instead

The probiotic market generates $10 billion per year despite evidence that most commercial supplements don't persist in the gut. Here's what the studies say—and five mechanistically stronger alternatives.

· 3 min

Dry Fasting for 5 Days: What the Biometrics Actually Showed

A measured 5-day dry fast tracked with continuous glucose, ketones, HRV, InBody scans, and grip strength. What the data showed — and what the dehydration artifact gets wrong.

· 3 min

99% of Probiotics Don't Colonize Your Gut. Here's What Actually Works.

The probiotic supplement market is projected to hit $10 billion by 2028 — and the evidence suggests most products fail to deliver meaningful gut benefits. A breakdown of what the science actually says and five evidence-backed alternatives to consider.

· 3 min

RLT Home TotalSpectrum Panels: Lab-Tested 7-Wavelength Review (2026)

A spectrometer test of RLT Home's ELITE panel measured 70.75 mW/cm² irradiance and 0.7 mG EMF at 12 inches, strong numbers for a full-body panel.

· 3 min

Home Infrared Sauna Buying Guide: The Three Specs That Actually Matter

The infrared sauna market spans $200 blankets to $15,000 cabins. Most buyers choose wrong by focusing on wood and aesthetics. Three specs determine whether a unit delivers results.

· 3 min

Fountain Life's $595 BASE Plan Is the Longevity Industry's Mass-Market Moment

Fountain Life's new BASE membership brings 100+ biomarkers, DEXA scan, and AI-guided clinician review to individuals for $595 — a significant shift from its ultra-premium roots.

· 2 min

Medtronic and Corsano Are Building the Hospital-to-Home Wearable Stack

Medtronic's integration of Corsano's FDA-cleared multi-parameter wearable into its HealthCast platform extends clinical monitoring from pre-op through home recovery — targeting alarm fatigue along the way.

· 2 min

C15:0: The Saturated Fat That Longevity Researchers Are Rethinking

Pentadecanoic acid — an odd-chain saturated fatty acid — is showing geroprotective properties that challenge blanket warnings against saturated fat, with initial research from Navy dolphin aging studies.

· 2 min

SystemAge 2.1: The First Biological Age Test with Separate Male and Female Models

Generation Lab's SystemAge 2.1 analyzes 460+ biomarkers across 21 organ systems using gender-specific algorithms — the most granular biological age measurement now available through clinical partners.

· 3 min

GARM's Klotho Longevity Residency Brought 22 Participants to Honduras. Here's What They're Testing.

A four-day longevity residency at the Kimpton Grand Roatán included a proprietary Klotho intervention, blood sampling before and after, and researchers from MIT and Harvard. GARM is betting that Klotho is the next longevity biomarker to watch.

· 4 min

Peter Attia: High HDL Cholesterol Doesn't Protect Your Heart. It Might Hurt It.

HDL-C has been called 'good cholesterol' for decades. Peter Attia's latest analysis unpacks why the clinical evidence never supported the label — and why very high HDL-C levels may signal elevated cardiovascular risk, not lower.

· 3 min

Lung Cancer Screening for Never-Smokers: What the Data Says

Guidelines don't recommend lung cancer screening for never-smokers — but the evidence gap is a policy artifact, not a scientific finding. Peter Attia makes the case for personalized assessment.

· 2 min

Rapalogix: $20M to Bring Rapamycin Anti-Aging Science to Skincare

Rapalogix Health raised a $20M Series A to expand rapamycin-based skincare targeting TORC1 — the cellular pathway behind systemic longevity interventions, now applied topically.

· 2 min

Menopause Tracking: Why the Average Is 9 Symptoms, Not 1 or 2

A Winona study of 100,000+ women found an average of nine simultaneous menopause symptoms — and 77.5% waited over a year before accessing care. The data reframes how practitioners should think about this life stage.

· 3 min

Your Complete Genome for $599: Human Longevity Inc. Bets on Consumer Genomics

Human Longevity Inc. now offers full whole-genome sequencing for $599 — down from ~$10,000 a decade ago — bundled with AI-powered multi-omics analysis across more than 50,000 conditions.

· 3 min

Ultrahuman M2 Live Makes Continuous Glucose Monitoring Mainstream

Ultrahuman's M2 Live pairs with Abbott's OTC Lingo CGM to bring prescription-free glucose tracking to anyone for $99/month — removing the biggest barrier to metabolic health monitoring.

· 3 min

Beacon Biosignals: AI Sleep Staging Is Moving Out of the Lab

Beacon Biosignals presented clinical validation data for its AI sleep staging algorithms at SLEEP 2026. What their EEG foundation model means for where consumer sleep tech is headed.

· 2 min

Nuritas' AI-Discovered Peptides Are Now in Frozen Yogurt — and 31 Countries

Nuritas uses AI to discover functional peptides from plant proteins, then validates them through clinical research. At IFT FIRST 2026, PeptiStrong arrived in frozen yogurt format. What this means for functional nutrition.

· 2 min

Why Smart People Believe Bad Health Advice: The Cognitive Bias Map

Intelligence doesn't protect against health misinformation — it often amplifies it. Here's the framework for recognizing which cognitive traps are most likely to corrupt your health decision-making.

· 4 min

Clair Raises $11.6M to Build the First Continuous Hormone Monitor for Women

Clair's wrist-worn device uses 10 biosensors and 130+ proprietary biomarkers to infer estrogen, progesterone, LH, and FSH levels in real time — revealing 9 distinct hormonal sub-phases the traditional 4-phase model misses.

· 3 min

Forever Chemicals Are Accelerating Your Biological Age — Longevity Needs to Catch Up

Two peer-reviewed studies link PFAS exposure to accelerated epigenetic aging via C-reactive protein. The longevity field's focus on what to add ignores what to remove — and that gap is measurable.

· 3 min

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